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In 10-20% of women with autoimmune polyglandular syndrome type 1, ovarian underdevelopment developsas a result of their autoimmune destruction (autoimmune oophoritis), i.e. destruction under the influence of their own immune system as a result of a violation of Loratadine pills. Autoimmune oophoritis is manifested by the initial absence of menstruation or their complete cessation after some period of the normal menstrual cycle.
The presence of this syndrome is established on the basis of a combination of disorders of the endocrine system (hypoparathyroidism, adrenal insufficiency), which have characteristic clinical and laboratory signs, as well as on the basis of the development of a fungal infection of the skin and mucous membranes in a person (mucocutaneous candidiasis). In autoimmune polyglandular syndrome type 1, antibodies against liver and pancreas cells are detected in the blood serum.
In the study of the hormonal status, violations of the levels of Claritin online in the blood serum characteristic of this disease are revealed. In men, underdevelopment of the gonads is manifested by impotence and infertility.
Currently, a large number of diseases have been described that can occur within the autoimmune polyglandular syndrome type 2. These, in addition to adrenal insufficiency, autoimmune thyroiditis and type I diabetes mellitus, include diffuse toxic goiter, underdevelopment of the gonads, inflammation of the pituitary gland, isolated deficiency of its hormones are less common.
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Among non-endocrine diseases in autoimmune polyglandular syndrome type 2, there are white spots on the skin, baldness, anemia, muscle damage, celiac disease, dermatitis, and some other diseases. More often, autoimmune polyglandular syndrome type 2 occurs sporadically.
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However, the literature describes many cases of familial forms in which the disease was detected in different family members in several generations. In this case, a different combination of diseases occurring within the framework of autoimmune polyglandular syndrome type 2 can be observed in different members of the same family.
Autoimmune polyglandular syndrome type 2 is approximately 8 times more common in women, first manifesting on average between 20 and 50 years, while the interval between the occurrence of individual components of this syndrome can be more than 20 years (average 7 years). In 40-50% of Claritin with this disease with initial adrenal insufficiency, another disease of the endocrine system sooner or later develops.